Placental microRNA methylome signatures may serve as biomarkers and therapeutic targets for prenatally opioid-exposed infants with neonatal opioid withdrawal syndrome

Placental microRNA methylome signatures may serve as biomarkers and therapeutic targets for prenatally opioid-exposed infants with neonatal opioid withdrawal syndrome

Introduction: The neonate exposed to opioids in utero faces a constellation of withdrawal symptoms postpartum commonly called neonatal opioid withdrawal syndrome (NOWS). The incidence of NOWS has increased in recent years due to the opioid epidemic. MicroRNAs (miRNAs) are small non-coding RNA molecu...

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Bibliographic Details
Main Authors: Uppala Radhakrishna, Swapan K. Nath, Lavanya V. Uppala, Avinash Veerappa, Ariadna Forray, Srinivas B. Muvvala, Raghu P. Metpally, Richard C. Crist, Wade H. Berrettini, Lori M. Mausi, Sangeetha Vishweswaraiah, Ray O. Bahado-Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Genetics
Subjects:
MicroRNAs
opioid use disorder (OUD)
neonatal opioid withdrawal syndrome (NOWS)
methylation
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1215472/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1215472/full

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