The Protective Role of TLR2 Mediates Impaired Autophagic Flux by Activating the mTOR Pathway During Neospora caninum Infection in Mice

The Protective Role of TLR2 Mediates Impaired Autophagic Flux by Activating the mTOR Pathway During Neospora caninum Infection in Mice

Autophagy has been shown to play an essential role in defending against intracellular bacteria, viruses, and parasites. Mounting evidence suggests that autophagy plays different roles in the infection process of different pathogens. Until now, there has been no conclusive evidence regarding whether...

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Bibliographic Details
Main Authors: Jielin Wang, Xiaocen Wang, Pengtao Gong, Fu Ren, Xin Li, Nan Zhang, Xu Zhang, Xichen Zhang, Jianhua Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Neospora caninum
autophagy
mTOR
TLR2
anti-infection
innate immune
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.788340/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.788340/full

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