Catalpol Protects ARPE-19 Cells against Oxidative Stress via Activation of the Keap1/Nrf2/ARE Pathway

Catalpol Protects ARPE-19 Cells against Oxidative Stress via Activation of the Keap1/Nrf2/ARE Pathway

Oxidative damage to retinal pigment epithelial (RPE) has been identified as one of the major regulatory factors in the pathogenesis of age-related macular degeneration (AMD). Catalpol is an iridoid glucoside compound that has been found to possess potential antioxidant activity. In the present study...

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Bibliographic Details
Main Authors: Longtai You, Hulinyue Peng, Jing Liu, Mengru Cai, Huimin Wu, Zhiqin Zhang, Jie Bai, Yu Yao, Xiaoxv Dong, Xingbin Yin, Jian Ni
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
catalpol
oxidative stress
Nrf2
apoptosis
cell cycle arrest
age-related macular degeneration
Online Access:https://www.mdpi.com/2073-4409/10/10/2635

Internet

https://www.mdpi.com/2073-4409/10/10/2635

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