Ethyl-acetate fraction from a cinnamon-cortex extract protects pancreatic β-cells from oxidative stress damage

Ethyl-acetate fraction from a cinnamon-cortex extract protects pancreatic β-cells from oxidative stress damage

Background: The pathogenesis of diabetes mellitus is mediated mainly by oxidative stress produced by damaged pancreatic β-cells. We identified that an ethyl-acetate fraction (EA) from a cinnamon-cortex extract (CCE) is rich in flavonoid, and showed no toxicity to β cells.Objective: In this study, we...

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Bibliographic Details
Main Authors: Weiling Li, Jialu Qiao, Kuan Lin, Ping Sun, Yuansong Wang, Qian Peng, Xiansheng Ye, Wei Liu, Binlian Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
PDX-1
antioxidant activity
apoptosis
pancreatic β cell
cinnamon cortex
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1111860/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1111860/full

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