A Straightforward Approach to Synthesize 7-Aminocephalosporanic Acid In Vivo in the Cephalosporin C Producer <i>Acremonium chrysogenum</i>

The pharmaceutical industry has developed various highly effective semi-synthetic cephalosporins, which are generated by modifying the side chains of the core molecule 7-aminocephalosporanic acid (7-ACA). In industrial productions, the 7-ACA nucleus is obtained in vitro from cephalosporin C (CPC) by...

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Bibliographic Details
Main Authors: Xuemei Lin, Jan Lambertz, Tim A. Dahlmann, Marc M. Nowaczyk, Burghard König, Ulrich Kück
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/8/5/450