Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis
The Rab27 effectors are known to play versatile roles in regulated exocytosis. In pancreatic beta cells, exophilin-8 anchors granules in the peripheral actin cortex, whereas granuphilin and melanophilin mediate granule fusion with and without stable docking to the plasma membrane, respectively. Howe...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2023-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/82821 |