Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis

The Rab27 effectors are known to play versatile roles in regulated exocytosis. In pancreatic beta cells, exophilin-8 anchors granules in the peripheral actin cortex, whereas granuphilin and melanophilin mediate granule fusion with and without stable docking to the plasma membrane, respectively. Howe...

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Bibliographic Details
Main Authors: Kunli Zhao, Kohichi Matsunaga, Kouichi Mizuno, Hao Wang, Katsuhide Okunishi, Tetsuro Izumi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/82821