Insight into Bortezomib Focusing on Its Efficacy against P-gp-Positive MDR Leukemia Cells
In this paper, we compared the effects of bortezomib on L1210 (S) cells with its effects on P-glycoprotein (P-gp)-positive variant S cells, which expressed P-gp either after selection with vincristine (R cells) or after transfection with a human gene encoding P-gp (T cells). Bortezomib induced the d...
Main Authors: | Tomáš Kyca, Lucia Pavlíková, Viera Boháčová, Anton Mišák, Alexandra Poturnayová, Albert Breier, Zdena Sulová, Mário Šereš |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-05-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/11/5504 |
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