The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models
Animal models of Parkinson’s disease, in which the human α-synuclein transgene is overexpressed in the nigrostriatal pathway using viral vectors, are widely considered to be the most relevant models of the human condition. However, although highly valid, these models have major limitations related t...
Những tác giả chính: | , , , , , , , , |
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Định dạng: | Bài viết |
Ngôn ngữ: | English |
Được phát hành: |
MDPI AG
2021-11-01
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Loạt: | Biomolecules |
Những chủ đề: | |
Truy cập trực tuyến: | https://www.mdpi.com/2218-273X/11/11/1685 |