Challenges in Discovering Drugs That Target the Protein–Protein Interactions of Disordered Proteins

Protein–protein interactions (PPIs) outnumber proteins and are crucial to many fundamental processes; in consequence, PPIs are associated with several pathological conditions including neurodegeneration and modulating them by drugs constitutes a potentially major class of therapy. Classically, howev...

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Bibliographic Details
Main Authors: Judit Oláh, Tibor Szénási, Attila Lehotzky, Victor Norris, Judit Ovádi
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/3/1550