Peptides disrupting TM4SF3 interaction with AR or AR-V7 block prostate cancer cell proliferation

Androgen receptor (AR) plays a vital role in the development and progression of prostate cancer from the primary stage to the usually lethal stage known as castration-resistant prostate cancer (CRPC). Constitutively active AR splice variants (AR-Vs) lacking the ligand-binding domain are partially re...

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Bibliographic Details
Main Authors: Prabesh Khatiwada, Ujjwal Rimal, Mamata Malla, Zhengyang Han, Lirim Shemshedini
Format: Article
Language:English
Published: Bioscientifica 2023-10-01
Series:Endocrine Oncology
Subjects:
Online Access:https://eo.bioscientifica.com/view/journals/eo/3/1/EO-23-0010.xml