Intestinal Inflammation and Alterations in the Gut Microbiota in Cystic Fibrosis: A Review of the Current Evidence, Pathophysiology and Future Directions

Intestinal Inflammation and Alterations in the Gut Microbiota in Cystic Fibrosis: A Review of the Current Evidence, Pathophysiology and Future Directions

Cystic fibrosis (CF) is a life-limiting autosomal recessive multisystem disease. While its burden of morbidity and mortality is classically associated with pulmonary disease, CF also profoundly affects the gastrointestinal (GI) tract. Chronic low-grade inflammation and alterations to the gut microbi...

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Bibliographic Details
Main Authors: Rachel Y. Tam, Josie M. van Dorst, Isabelle McKay, Michael Coffey, Chee Y. Ooi
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Journal of Clinical Medicine
Subjects:
cystic fibrosis
gastrointestinal tract
intestinal inflammation
gut microbiome
dysbiosis
Online Access:https://www.mdpi.com/2077-0383/11/3/649

Internet

https://www.mdpi.com/2077-0383/11/3/649

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