Expression of Immunomodulatory Checkpoint Molecules in Drug-Resistant Neuroblastoma: An Exploratory Study

Expression of Immunomodulatory Checkpoint Molecules in Drug-Resistant Neuroblastoma: An Exploratory Study

Neuroblastoma is a common childhood cancer with poor prognosis when at its advanced stage. Checkpoint molecule inhibition is successful in treating multiple advanced adult cancers. We investigated PD-L1 and other checkpoint molecule expression to determine their roles in drug resistance and usefulne...

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Bibliographic Details
Main Authors: Nicholas J. Skertich, Fei Chu, Imad A. M. Tarhoni, Stephen Szajek, Jeffrey A. Borgia, Mary Beth Madonna
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
neuroblastoma
doxorubicin
drug resistance
programmed death ligand 1
checkpoint protein molecules
checkpoint molecule inhibition
Online Access:https://www.mdpi.com/2072-6694/14/3/751

Internet

https://www.mdpi.com/2072-6694/14/3/751

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