Should Preimplantation Genetic Testing (PGT) Systematically Be Proposed to <i>BRCA</i> Pathogenic Variant Carriers?

Should Preimplantation Genetic Testing (PGT) Systematically Be Proposed to <i>BRCA</i> Pathogenic Variant Carriers?

Over the past years, <i>BRCA</i> genes pathogenic variants have been associated to reproductive issues. Indeed, evidence indicate that <i>BRCA</i>-mutated patients are not only at higher risk of developing malignancies, but may also present a reduction of the follicular stock...

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Bibliographic Details
Main Authors: Lucie Laot, Charlotte Sonigo, Julie Nobre, Alexandra Benachi, Traicie Dervin, Lina El Moujahed, Anne Mayeur, Dominique Stoppa-Lyonnet, Julie Steffann, Michael Grynberg
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
<i>BRCA</i> pathogenic variant
preimplantation genetic testing
fertility preservation
Online Access:https://www.mdpi.com/2072-6694/14/23/5769

Internet

https://www.mdpi.com/2072-6694/14/23/5769

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