Alkali-treated titanium dioxide promotes formation of proteoglycan layer and altered calcification and immunotolerance capacity in bone marrow stem cell

Alkali-treated titanium dioxide promotes formation of proteoglycan layer and altered calcification and immunotolerance capacity in bone marrow stem cell

Introduction: In this study, we report that a proteoglycans (PGs)-layer between the bone and titanium dioxide (TiO2) surface after osseointegration improved the calcification capacity and immunotolerance of human bone marrow mesenchymal stem cells (hBMSCs) on TiO2. Alkaline treatment of TiO2 is a me...

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Bibliographic Details
Main Authors: Tomomi Mizutani, Shuhei Tsuchiya, Masaki Honda, Jorge Luis Montenegro Raudales, Kensuke Kuroda, Hironori Miyamoto, Tomohisa Nakamura, Kenichiro Ishibashi, Yasuyuki Shibuya
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Alkaline treatment
Titanium dioxide
Proteoglycan
Immunotolerance
T-cell
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823001504

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http://www.sciencedirect.com/science/article/pii/S2405580823001504

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