Development of a Competition-Binding Assay to Determine Binding Affinity of Molecules to Neuromelanin via Fluorescence Spectroscopy

Neuromelanin, the polymeric form of dopamine which accumulates in aging neuronal tissue, is increasingly recognized as a functional and critical component of a healthy and active adult human brain. Notorious in plant and insect literature for their ability to bind and retain amines for long periods...

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Bibliographic Details
Main Authors: Jackson Fink, Heather Pathak, John Smith, Cindy Achat-Mendes, Robert L. Haining
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/5/175