Apolipoprotein E knockout may affect cognitive function in D-galactose-induced aging mice through the gut microbiota–brain axis

Apolipoprotein E knockout may affect cognitive function in D-galactose-induced aging mice through the gut microbiota–brain axis

The gut microbiota plays an important role in central nervous system (CNS) disorders. Apolipoprotein E (ApoE) can affect the composition of the gut microbiota and is closely related to the CNS. However, the mechanism by which ApoE affects cognitive dysfunction through the gut microbiota–brain axis h...

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Bibliographic Details
Main Authors: Bowei Chen, Jian Yi, Yaqian Xu, Huiqiao Wen, Fengming Tian, Yingfei Liu, Lan Xiao, Lisong Li, Baiyan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Neuroscience
Subjects:
apolipoprotein E
aging
cognitive function
gut microbiota
metabolomics
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.939915/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.939915/full

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