Unravelling Novel <i>SCN5A</i> Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights

Unravelling Novel <i>SCN5A</i> Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights

Brugada Syndrome (BrS) is a rare inherited cardiac arrhythmia causing potentially fatal ventricular tachycardia or fibrillation, mainly occurring during rest or sleep in young individuals without heart structural issues. It increases the risk of sudden cardiac death, and its characteristic feature i...

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Bibliographic Details
Main Authors: Anthony Frosio, Emanuele Micaglio, Ivan Polsinelli, Serena Calamaio, Dario Melgari, Rachele Prevostini, Andrea Ghiroldi, Anna Binda, Paola Carrera, Marco Villa, Flavio Mastrocinque, Silvia Presi, Raffaele Salerno, Antonio Boccellino, Luigi Anastasia, Giuseppe Ciconte, Stefano Ricagno, Carlo Pappone, Ilaria Rivolta
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
Brugada syndrome
sudden cardiac death
arrhythmias
sodium channel
Nav1.5
<i>SCN5A</i>
Online Access:https://www.mdpi.com/1422-0067/24/20/15089

Internet

https://www.mdpi.com/1422-0067/24/20/15089

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