Towards a molecular classification of colorectal cancer:The role of microsatellite instability status
Microsatellite instability (MSI) is the molecular hallmark of DNA mismatch repair (MMR) deficiency. Since its initial description in colorectal cancer (CRC) in 1993 and its association with Lynch syndrome, the most common inherited cancer predisposition world-wide, accumulating evidence suggests tha...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-10-01
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| Series: | Frontiers in Oncology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00272/full |