Evaluating the impact of sequencing depth on transcriptome profiling in human adipose.

Recent advances in RNA sequencing (RNA-Seq) have enabled the discovery of novel transcriptomic variations that are not possible with traditional microarray-based methods. Tissue and cell specific transcriptome changes during pathophysiological stress in disease cases versus controls and in response...

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Bibliographic Details
Main Authors: Yichuan Liu, Jane F Ferguson, Chenyi Xue, Ian M Silverman, Brian Gregory, Muredach P Reilly, Mingyao Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3691247?pdf=render