Pterostilbene Activates the Nrf2-Dependent Antioxidant Response to Ameliorate Arsenic-Induced Intracellular Damage and Apoptosis in Human Keratinocytes

Pterostilbene Activates the Nrf2-Dependent Antioxidant Response to Ameliorate Arsenic-Induced Intracellular Damage and Apoptosis in Human Keratinocytes

The NF-E2 p45-related factor 2 (Nrf2), a transcription factor that regulates the cellular adaptive response to oxidative stress, is a target for limiting tissue damage from exposure to environmental toxins, including arsenic. In the current study, we determine whether Pterostilbene (Pts), as a poten...

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Bibliographic Details
Main Authors: Junfeng Zhou, Xinxin Ci, Xiaoyuan Ma, Qinlei Yu, Yan Cui, Yu Zhen, Shanshan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Pharmacology
Subjects:
pterostilbene
Nrf2
arsenic
apoptosis
keratinocytes
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00497/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00497/full

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