Dissection of a complex transcriptional response using genome‐wide transcriptional modelling

Dissection of a complex transcriptional response using genome‐wide transcriptional modelling

Abstract Modern genomics technologies generate huge data sets creating a demand for systems level, experimentally verified, analysis techniques. We examined the transcriptional response to DNA damage in a human T cell line (MOLT4) using microarrays. By measuring both mRNA accumulation and degradatio...

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Bibliographic Details
Main Authors: Martino Barenco, Daniel Brewer, Efterpi Papouli, Daniela Tomescu, Robin Callard, Jaroslav Stark, Michael Hubank
Format: Article
Language:English
Published: Springer Nature 2009-11-01
Series:Molecular Systems Biology
Subjects:
modelling
transcription
microarrays
transcription factor activity
Online Access:https://doi.org/10.1038/msb.2009.84

Internet

https://doi.org/10.1038/msb.2009.84

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