Ageing-Related Changes to H3K4me3, H3K27ac, and H3K27me3 in Purified Mouse Neurons

Neurons are central to lifelong learning and memory, but ageing disrupts their morphology and function, leading to cognitive decline. Although epigenetic mechanisms are known to play crucial roles in learning and memory, neuron-specific genome-wide epigenetic maps into old age remain scarce, often b...

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Bibliographic Details
Main Authors: Brandon Signal, Andrew J. Phipps, Katherine A. Giles, Shannon N. Huskins, Timothy R. Mercer, Mark D. Robinson, Adele Woodhouse, Phillippa C. Taberlay
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/16/1393