S-nitrosothiol homeostasis maintained by ADH5 facilitates STING-dependent host defense against pathogens

S-nitrosothiol homeostasis maintained by ADH5 facilitates STING-dependent host defense against pathogens

Abstract Oxidative (or respiratory) burst confers host defense against pathogens by generating reactive species, including reactive nitrogen species (RNS). The microbial infection-induced excessive RNS damages many biological molecules via S-nitrosothiol (SNO) accumulation. However, the mechanism by...

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Bibliographic Details
Main Authors: Mutian Jia, Li Chai, Jie Wang, Mengge Wang, Danhui Qin, Hui Song, Yue Fu, Chunyuan Zhao, Chengjiang Gao, Jihui Jia, Wei Zhao
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46212-z

Internet

https://doi.org/10.1038/s41467-024-46212-z

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