Histone modifications are associated with transcript isoform diversity in normal and cancer cells.
Mechanisms that generate transcript diversity are of fundamental importance in eukaryotes. Although a large fraction of human protein-coding genes and lincRNAs produce more than one mRNA isoform each, the regulation of this phenomenon is still incompletely understood. Much progress has been made in...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-06-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4046914?pdf=render |