Quantitative Nuclear Histomorphometry Predicts Molecular Subtype and Clinical Outcome in Medulloblastomas: Preliminary Findings

Quantitative Nuclear Histomorphometry Predicts Molecular Subtype and Clinical Outcome in Medulloblastomas: Preliminary Findings

Molecular subtypes of medulloblastoma [Sonic Hedgehog (SHH), Wingless/INT (WNT), Group 3, and Group 4] are defined by common patterns of gene expression. These differential gene expression patterns appear to result in different histomorphology and prognosis. Quantitative histomorphometry is a well-k...

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Bibliographic Details
Main Authors: Jon Whitney, Liisa Dollinger, Benita Tamrazi, Debra Hawes, Marta Couce, Julia Marcheque, Alexander Judkins, Ashley Margol, Anant Madabhushi
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Pathology Informatics
Online Access:http://www.sciencedirect.com/science/article/pii/S2153353922000906

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http://www.sciencedirect.com/science/article/pii/S2153353922000906

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