Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by <i>Escherichia coli</i>

Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by <i>Escherichia coli</i>

Tet methylcytosine dioxygenase 2 (Tet2) mediates demethylation of DNA. We here sought to determine the expression and function of Tet2 in macrophages upon exposure to lipopolysaccharide (LPS), and in the host response to LPS induced lung and peritoneal inflammation, and during <i>Escherichia (...

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Bibliographic Details
Main Authors: Wanhai Qin, Xanthe Brands, Hisatake Matsumoto, Joe M. Butler, Cornelis van’t Veer, Alex F. de Vos, Joris J. T. H. Roelofs, Brendon P. Scicluna, Tom van der Poll
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
TET2
macrophages
inflammation
infection
<i>E. coli</i>
Online Access:https://www.mdpi.com/2073-4409/11/1/82

Internet

https://www.mdpi.com/2073-4409/11/1/82

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