Endothelin-1 and Its Role in Cancer and Potential Therapeutic Opportunities

Endothelin-1 (ET-1) plays a physiological role as a potent vasoconstrictor. It is implicated in an array of diseases, and its signalling is often found to be overactivated within cancers. ET-1 has been found to potentiate hallmarks of cancer progression such as cell proliferation, invasion and metas...

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Bibliographic Details
Main Authors: Madeline Harrison, Dmitry Zinovkin, Md Zahidul Islam Pranjol
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/12/3/511