Synthesis of Stable Isotope Deuterium Labeled Levofloxacin-D3

In order to improve the stable isotope utilization rate, a simple and inexpensive synthesis method was developed. The synthesis of levofloxacin is based on piperazine as the starting material, and the reaction with carbobenzoxy chloride (CBZ-Cl) to get CBZ-piperazine-CD3, and then the reaction with...

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Bibliographic Details
Main Author: XU Zhong jie;ZHANG Li;SUN Wen;ZHANG Pengshuai;LEI Wen
Format: Article
Language:zho
Published: Editorial Board of Journal of Isotopes 2023-02-01
Series:Journal of Isotopes
Subjects:
Online Access:http://www.tws.org.cn/CN/10.7538/tws.2023.36.02.0144