Neuron Contact Detection Based on Pipette Precise Positioning for Robotic Brain-Slice Patch Clamps

A patch clamp is the “gold standard” method for studying ion-channel biophysics and pharmacology. Due to the complexity of the operation and the heavy reliance on experimenter experience, more and more researchers are focusing on patch-clamp automation. The existing automated patch-clamp system focu...

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Bibliographic Details
Main Authors: Ke Li, Huiying Gong, Jinyu Qiu, Ruimin Li, Qili Zhao, Xin Zhao, Mingzhu Sun
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/23/19/8144