An ACE2-Based Decoy Inhibitor Effectively Neutralizes SARS-CoV-2 Omicron BA.5 Variant

An ACE2-Based Decoy Inhibitor Effectively Neutralizes SARS-CoV-2 Omicron BA.5 Variant

The recently circulating SARS-CoV-2 Omicron BA.5 is rampaging the world with elevated transmissibility compared to the original SARS-CoV-2 strain. Immune escape of BA.5 was observed after treatment with many monoclonal antibodies, calling for broad-spectrum, immune-escape-evading therapeutics. In re...

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Bibliographic Details
Main Authors: Haoran Zhang, Bing Hu, Panjing Lv, Yahui Liu, Meng Guo, Zhi Wu, Kangping Zhou, Minglu Dai, Xiao Yu, Zhang Liu, Bo Yu, Liqiong Xu, Min Guo, Kun Cai, Yan Li
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
SARS-CoV-2
Omicron BA.5
protein antagonist
ACE2
neutralization escape
Online Access:https://www.mdpi.com/1999-4915/14/11/2387

Internet

https://www.mdpi.com/1999-4915/14/11/2387

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