Identifying molecular targets of Aspiletrein-derived steroidal saponins in lung cancer using network pharmacology and molecular docking-based assessments

Abstract Lung cancer is one of the leading cancers and causes of cancer-related deaths worldwide. Due to its high prevalence and mortality rate, its clinical management remains a significant challenge. Previously, the in vitro anticancer activity of Aspiletrein A, a steroid and a saponin from Aspidi...

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Bibliographic Details
Main Authors: Iksen Iksen, Wasita Witayateeraporn, Tanakrit Wirojwongchai, Chutipa Suraphan, Natapol Pornputtapong, Natsaranyatron Singharajkomron, Hien Minh Nguyen, Varisa Pongrakhananon
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28821-8