Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay.

Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay.

Candida albicans, the most common human pathogenic fungus, can establish a persistent lethal infection in the intestine of the microscopic nematode Caenorhabditis elegans. The C. elegans-C. albicans infection model was previously adapted to screen for antifungal compounds. Modifications to this scre...

Full description

Bibliographic Details
Main Authors: Ikechukwu Okoli, Jeffrey J Coleman, Emmanouil Tampakakis, W Frank An, Edward Holson, Florence Wagner, Annie L Conery, Jonah Larkins-Ford, Gang Wu, Andy Stern, Frederick M Ausubel, Eleftherios Mylonakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2737148?pdf=render

Internet

http://europepmc.org/articles/PMC2737148?pdf=render

Similar Items