Topics on the Na+/Ca2+ Exchanger: Involvement of Na+/Ca2+ Exchanger in the Vasodilator-Induced Vasorelaxation

Many kinds of vasodilators induce relaxation of the vascular smooth muscle cells (VSMCs) through the production of cyclic AMP (cAMP) or cyclic GMP (cGMP). The relaxant effects mediated by these second messengers are thought to be mainly due to the decrease in intracellular Ca2+ concentration ([Ca2+]...

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Bibliographic Details
Main Author: Junji Nishimura
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344123