A transistor model for the cystic fibrosis transmembrane conductance regulator

In this paper we present a transistor circuit model for cystic fibrosis transmembrane conductance regulator (CFTR) that seeks to map the functional form of CFTR both in wild type and mutants. The circuit architecture is configured so that the function, and as much as possible the form, faithfully re...

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Bibliographic Details
Main Authors: William D. Hunt, Nael A. McCarty, Eduardo Martinez Marin, Ryan S. Westafer, Phillip R. Yamin, Guiying Cui, Andrew W. Eckford, Douglas R. Denison
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Biophysical Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2667074723000095