A transistor model for the cystic fibrosis transmembrane conductance regulator
In this paper we present a transistor circuit model for cystic fibrosis transmembrane conductance regulator (CFTR) that seeks to map the functional form of CFTR both in wild type and mutants. The circuit architecture is configured so that the function, and as much as possible the form, faithfully re...
Main Authors: | William D. Hunt, Nael A. McCarty, Eduardo Martinez Marin, Ryan S. Westafer, Phillip R. Yamin, Guiying Cui, Andrew W. Eckford, Douglas R. Denison |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | Biophysical Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667074723000095 |
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