Tolvaptan in Pediatric Autosomal Dominant Polycystic Kidney Disease: From Here to Where?

Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder, accounting for approximately 5% of all ESRD cases worldwide. As a vasopressin receptor 2 antagonist, tolvaptan is the FDA-approved therapeutic agent for ADPKD, which is only made available...

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Bibliographic Details
Main Authors: Fei Liu, Chunyue Feng, Huijun Shen, Huaidong Fu, Jianhua Mao
Format: Article
Language:English
Published: Karger Publishers 2021-07-01
Series:Kidney Diseases
Subjects:
Online Access:https://www.karger.com/Article/FullText/517186