Integration of Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanisms of Zhuanggu Busui Formula Against Osteoporosis

Integration of Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanisms of Zhuanggu Busui Formula Against Osteoporosis

Osteoporosis (OP) is a common skeletal disease, characterized by decreased bone formation and increased bone resorption. As a novel Chinese medicine formula, Zhuanggu Busui formula (ZGBSF) has been proved to be an effective prescription for treating OP in clinic, however, the pharmacological mechani...

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Bibliographic Details
Main Authors: Huihao Zhang, Chengcong Zhou, Zhiguo Zhang, Sai Yao, Yishan Bian, Fangda Fu, Huan Luo, Yan Li, Shuxin Yan, Yuying Ge, Yuying Chen, Kunyu Zhan, Ming Yue, Weibin Du, Kun Tian, Hongting Jin, Xiaofeng Li, Peijian Tong, Hongfeng Ruan, Chengliang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Endocrinology
Subjects:
osteoporosis
Zhuanggu Busui formula
network pharmacology
pharmacological mechanisms
apoptosis
PI3K-Akt signalling
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.841668/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.841668/full

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