Error estimates for the analysis of differential expression from RNA-seq count data
Background. A number of algorithms exist for analysing RNA-sequencing data to infer profiles of differential gene expression. Problems inherent in building algorithms around statistical models of over dispersed count data are formidable and frequently lead to non-uniform p-value distributions for nu...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2014-09-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/576.pdf |