Multivariate optimization for simultaneous determination of aspirin and simvastatin by reverse phase liquid chromatographic method using AQbD approach
The present study describes the development of a robust method for the separation of aspirin and simvastatin using reverse phase high performance liquid chromatographic method on Kintex reverse phase C18 column (5 μm, 250 mm Ã 4.6 mm) with UV detection at 234 nm. Box-Behnken design was applie...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Pharmacy, Cairo University
2017-12-01
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| Series: | Bulletin of Faculty of Pharmacy Cairo University |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110093117300388 |