Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay.

Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay.

Endocrine resistance is a major problem with anti-estrogen treatments and how to overcome resistance is a major concern in the clinic. Reliable measurement of cell viability, proliferation, growth inhibition and death is important in screening for drug treatment efficacy in vitro. This report descri...

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Bibliographic Details
Main Authors: Eileen M McGowan, Nikki Alling, Elise A Jackson, Daniel Yagoub, Nikolas K Haass, John D Allen, Rosetta Martinello-Wilks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3108819?pdf=render

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http://europepmc.org/articles/PMC3108819?pdf=render

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