In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats

In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats

Abstract Background Emerging evidence suggests that specific (poly)phenols may constitute new preventative strategies to counteract cell oxidative stress and myocardial tissue inflammation, which have a key role in the patho-physiology of diabetic cardiomyopathy. In a rat model of early diabetes, we...

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Bibliographic Details
Main Authors: Monia Savi, Leonardo Bocchi, Pedro Mena, Margherita Dall’Asta, Alan Crozier, Furio Brighenti, Donatella Stilli, Daniele Del Rio
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Cardiovascular Diabetology
Subjects:
Diabetes
Ellagitannins
Cardiac performance
Cardiomyocyte mechanics
Urolithins
Online Access:http://link.springer.com/article/10.1186/s12933-017-0561-3

Internet

http://link.springer.com/article/10.1186/s12933-017-0561-3

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