Facile hyperpolarization chemistry for molecular imaging and metabolic tracking of [1–13C]pyruvate in vivo

Facile hyperpolarization chemistry for molecular imaging and metabolic tracking of [1–13C]pyruvate in vivo

Hyperpolarization chemistry based on reversible exchange of parahydrogen, also known as Signal Amplification By Reversible Exchange (SABRE), is a particularly simple approach to attain high levels of nuclear spin hyperpolarization, which can enhance NMR and MRI signals by many orders of magnitude. S...

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Bibliographic Details
Main Authors: Keilian MacCulloch, Austin Browning, David O. Guarin Bedoya, Stephen J. McBride, Mustapha B. Abdulmojeed, Carlos Dedesma, Boyd M. Goodson, Matthew S. Rosen, Eduard Y. Chekmenev, Yi-Fen Yen, Patrick TomHon, Thomas Theis
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Magnetic Resonance Open
Subjects:
Hyperpolarized MRI
Parahydrogen
SABRE
Metabolic imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2666441023000377

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http://www.sciencedirect.com/science/article/pii/S2666441023000377

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