An Automated Continuous Synthesis and Isolation for the Scalable Production of Aryl Sulfonyl Chlorides

An Automated Continuous Synthesis and Isolation for the Scalable Production of Aryl Sulfonyl Chlorides

In this work, a continuous system to produce multi-hundred-gram quantities of aryl sulfonyl chlorides is described. The scheme employs multiple continuous stirred-tank reactors (CSTRs) and a continuous filtration system and incorporates an automated process control scheme. The experimental process o...

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Bibliographic Details
Main Authors: Matthew Glace, Cameron Armstrong, Nathan Puryear, Colin Bailey, Roudabeh Sadat Moazeni-Pourasil, Drew Scott, Sherif Abdelwahed, Thomas. D. Roper
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
flow chemistry
chlorosulfonation
process automation
pump control system
continuous manufacturing
batch design
Online Access:https://www.mdpi.com/1420-3049/28/10/4213

Internet

https://www.mdpi.com/1420-3049/28/10/4213

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