CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signaling

IntroductionCXCL17 is a mucosally secreted protein, and the most recently identified human chemokine, an assignment based on protein fold prediction and chemotactic activity for leukocytes. However, these credentials have been the subject of much recent discussion and no experimental evidence has be...

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Main Authors: Sean P. Giblin, Sashini Ranawana, Shyreen Hassibi, Holly L. Birchenough, Kyle T. Mincham, Robert J. Snelgrove, Tomoko Tsuchiya, Shiro Kanegasaki, Douglas Dyer, James E. Pease
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1254697/full