Differential Incidence of Tongue Base Cancer in Male and Female HPV16-Transgenic Mice: Role of Female Sex Hormone Receptors

Differential Incidence of Tongue Base Cancer in Male and Female HPV16-Transgenic Mice: Role of Female Sex Hormone Receptors

A growing proportion of oropharyngeal squamous cell carcinomas (OPSCC) are associated with infection by high-risk human papillomavirus (HPV). For reasons that remain largely unknown, HPV+OPSCC is significantly more common in men than in women. This study aims to determine the incidence of OPSCC in m...

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Bibliographic Details
Main Authors: Clariano Pires de Oliveira Neto, Beatriz Medeiros-Fonseca, Diogo Estêvão, Verónica F. Mestre, Natália R. Costa, Fábio Evangelista de Andrade, Paula A. Oliveira, Margarida M. S. M. Bastos, Rui Medeiros, Diogo Assis, Ana Félix, Fernanda Ferreira Lopes, Rui M. Gil da Costa, Haissa O. Brito, Luciane M. O. Brito
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pathogens
Subjects:
estrogen receptor
progesterone receptor
collagen
matrix metalloproteinase
tongue base cancer
Online Access:https://www.mdpi.com/2076-0817/10/10/1224

Internet

https://www.mdpi.com/2076-0817/10/10/1224

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