All-<i>trans</i> Retinoic Acid and Beta-Carotene Increase Sclerostin Production in C2C12 Myotubes
Sclerostin is a protein secreted by osteocytes whose encoding gene <i>SOST</i> is regulated by mechanical stimuli, cytokines, and all-<i>trans</i> retinoic acid (ATRA) and mediates antianabolic effects on bone formation as an inhibitor of the canonical Wnt/β-catenin pathway....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-05-01
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| Series: | Biomedicines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9059/11/5/1432 |