Retinoic Acid Receptor Alpha Is Essential in Postnatal Sertoli Cells but Not in Germ Cells

Retinoic Acid Receptor Alpha Is Essential in Postnatal Sertoli Cells but Not in Germ Cells

Retinoic acid signaling is indispensable for the completion of spermatogenesis. It is known that loss of retinoic acid nuclear receptor alpha (RARA) induces male sterility due to seminiferous epithelium degeneration. Initial genetic studies established that RARA acts in Sertoli cells, but a recent p...

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Bibliographic Details
Main Authors: Diana Condrea, Sirine Souali-Crespo, Betty Féret, Muriel Klopfenstein, Sylvain Faisan, Manuel Mark, Norbert B. Ghyselinck, Nadège Vernet
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
anti-RARA antibodies for IHC
mouse
retinoic acid
Sertoli cell
seminiferous epithelium
Sox9-CreERT<sup>2</sup>
Online Access:https://www.mdpi.com/2073-4409/11/5/891

Internet

https://www.mdpi.com/2073-4409/11/5/891

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