Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites

Abstract Invasion of red blood cells (RBCs) by Plasmodium merozoites is critical to their continued survival within the host. Two major protein families, the Duffy binding-like proteins (DBPs/EBAs) and the reticulocyte binding like proteins (RBLs/RHs) have been studied extensively in P. falciparum a...

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Bibliographic Details
Main Authors: Melissa N. Hart, Franziska Mohring, Sophia M. DonVito, James A. Thomas, Nicole Muller-Sienerth, Gavin J. Wright, Ellen Knuepfer, Helen R. Saibil, Robert W. Moon
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40357-z