Nitazoxanide: A Drug Repositioning Compound with Potential Use in Chagas Disease in a Murine Model

Nitazoxanide: A Drug Repositioning Compound with Potential Use in Chagas Disease in a Murine Model

Chagas disease (ChD), caused by <i>Trypanosoma cruzi</i>, is the most serious parasitosis in the western hemisphere. Benznidazole and nifurtimox, the only two trypanocidal drugs, are expensive, difficult to obtain, and have severe side effects. Nitazoxanide has shown to be effective agai...

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Bibliographic Details
Main Authors: Minerva Arce-Fonseca, Rodolfo Andrés Gutiérrez-Ocejo, José Luis Rosales-Encina, Alberto Aranda-Fraustro, Juan José Cabrera-Mata, Olivia Rodríguez-Morales
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceuticals
Subjects:
Chagas disease
<i>Trypanosoma cruzi</i>
drug repositioning
anti-<i>T. cruzi</i> agent
nitazoxanide
mouse model
Online Access:https://www.mdpi.com/1424-8247/16/6/826

Internet

https://www.mdpi.com/1424-8247/16/6/826

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