Next Generation of Cancer Drug Repurposing: Therapeutic Combination of Aspirin and Oseltamivir Phosphate Potentiates Gemcitabine to Disable Key Survival Pathways Critical for Pancreatic Cancer Progression

Next Generation of Cancer Drug Repurposing: Therapeutic Combination of Aspirin and Oseltamivir Phosphate Potentiates Gemcitabine to Disable Key Survival Pathways Critical for Pancreatic Cancer Progression

Resistance to chemotherapeutics and high metastatic rates contribute to the abysmal survival rate in patients with pancreatic cancer. An alternate approach for treating human pancreatic cancer involves repurposing the anti-inflammatory drug, aspirin (ASA), with oseltamivir phosphate (OP) in combinat...

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Bibliographic Details
Main Authors: Bessi Qorri, Reza Bayat Mokhtari, William W. Harless, Myron R. Szewczuk
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
repurposed drugs
multimodal therapy
cancer therapy
drug repositioning
Online Access:https://www.mdpi.com/2072-6694/14/6/1374

Internet

https://www.mdpi.com/2072-6694/14/6/1374

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